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First results of bird flu vaccine trials expected in 2 weeks

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Provisional results of bird flu vaccine trials on human volunteers will be available in two weeks, one of the doctors leading the tests said Monday.

ST. PETERSBURG, June 5 (RIA Novosti) - Provisional results of bird flu vaccine trials on human volunteers will be available in two weeks, one of the doctors leading the tests said Monday.

Oleg Kiselyov, the director of the St. Petersburg-based Influenza Research Institute, said the trials were focusing on establishing a precise vaccine dose.

"The phrase 'vaccine tests' is not entirely appropriate," he said. "We are conducting trials to calculate the dosage."

Kiselyov said the vaccine presented no danger to the 52 volunteers who had received it intravenously.

Kiselyov said the volunteers would be revaccinated in 28 days from the date of the first vaccination to calculate the vaccine titers used to determine the highest dilution that still contained detectable amounts of antibody.

"The threshold limit [to prevent serious form of a disease] is 1/64, with the optimum level at 1/256," he said.

But he cautioned the vaccine had been created on the basis of a non-pandemic H5N1 bird flu strain and could not stop a pandemic of avian influenza.

"The substance is a reserve vaccine and will not become a panacea in the event of a bird flu pandemic," he said.

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