The ministry said the train had departed from Russia's 62nd military base in Akhalkalaki carrying combat support vehicles and trucks. It is the second train with military equipment to leave Georgia this year under an agreement Russia and Georgia signed March 31, 2006.
Russian troops and hardware are to completely withdraw from Georgia's two Soviet-era bases in Akhalkalaki and Batumi by 2008. The pullout from Akhalkalaki, about 30 kilometers (19 miles) from the border with NATO member Turkey, is to be completed by December 2006.
The withdrawal is being monitored by a joint Georgian-Russian commission set up under the March agreement. The next train is scheduled to leave Georgia on May 24.
The bulk of Russia's weapons will return to Russia and the rest of it will be delivered to a Russian base in Armenia.