Medvedev is to visit China on May 23-24.
"The package of documents is currently being discussed, and work will continue up to the visit," Sergei Razov said. "Among other things, an agreement on nuclear cooperation is expected to be signed."
He added that Medvedev would be accompanied by a group of Russian businessmen.
"The delegation will include a large group of representatives from Russian economic circles, and we do not rule out the signing of a number of contracts," Razov added.
During his visit, Medvedev, who was sworn in as president on May 7, will meet with Chinese President Hu Jintao, Prime Minister Wen Jiabao, and other high-ranking officials.
Medvedev is due to fly to China from Kazakhstan, where he will make his first foreign visit as Russian president.
