The summit in Riyadh, which will represent all of its 22 members except Libya, will focus on the Israeli-Palestinian conflict, the situation in Iraq, Lebanon and Syria, internal conflicts in Somalia and Sudan's Darfur region, and measures to prevent the proliferation of weapons of mass destruction in the region.
The delegates plan to discuss the renovation of the Arab Peace Initiative, a proposal adopted at the 2002 Beirut Summit seeking a comprehensive peace between Israel and Arab countries.
The initiative endorses an Israeli withdrawal from all territories occupied since the 1967 Arab-Israeli war and a just solution to the Palestinian refugee problem.
The refugee problem is felt particularly acutely in Lebanon, which shelters some 350,000 Palestinians but denies them citizenship for fear that the tenuous balance of different religious groups in the country could be disrupted.
Lebanon will be represented by two delegations - one headed by President Emile Lahoud, and the other by Prime Minister Fuad Siniora, who leads a parliamentary majority opposed to the president in a protracted political standoff in the country.
