The girl from Kafr el-Sheikh, in northern Egypt, was confirmed with the virus on Sunday. She is currently being treated in hospital, her condition is described as "stable."
This is the second case in a week of someone from northern Egypt contracting the deadly virus.
On Friday the health ministry said a woman was in hospital with the virus after coming into contact with sick poultry.
The latest case brings the number of reported cases of bird flu in Egypt to 66 this year.
As of April 8, a total of 417 bird flu cases had been registered worldwide since the virus was first detected in 2003, resulting in 257 deaths, according to the WHO.
Although there have been no incidences of human-to-human infection, experts fear that the bird flu virus may mutate into a form that could be easily transmitted from person to person, causing a global pandemic.
